Physiological Effects for Remote Pilots
Some manned-aviation physiology transfers straight over to Part 107. Some of it doesn't, and knowing which is which is the actual exam skill.
Physiology feels like an odd fit for a knowledge test about flying an aircraft you never board, and that mismatch is exactly the point: the test is checking whether you understand which physiological effects actually apply to a remote pilot standing on the ground, not just importing manned-aviation content wholesale.
The one that mostly doesn't apply: hypoxia
Manned-aviation physiology spends a lot of time on hypoxia, reduced oxygen affecting a pilot's judgment at altitude, because that pilot is breathing the air the aircraft is flying through. A remote pilot operating a small UAS, capped at 400 feet AGL under the base rule, stays on the ground the entire flight. The aircraft's altitude doesn't change what the pilot is breathing. Hypoxia isn't a meaningful risk factor for the remote pilot in the way it is for someone actually seated in a climbing aircraft, and exam material reflects that difference rather than treating sUAS operation as a smaller version of manned flight physiology.
The remote pilot's body never leaves the ground. Most of what matters here is what affects judgment and vision from there, not what affects a body at altitude.
What does apply, directly
Dehydration and heatstroke are real risks for a remote pilot standing outside for an extended operation, especially in hot weather, and both measurably degrade cognitive performance and reaction time well before someone would describe themselves as impaired. Hyperventilation, breathing faster and deeper than the body needs, typically triggered by stress or anxiety rather than altitude, produces dizziness, tingling, and confusion that can look like something else entirely if a pilot doesn't recognize the pattern. Stress and fatigue degrade decision-making in ways that compound with each other rather than staying independent problems.
400 ft AGL
the base-rule altitude ceiling that keeps hypoxia out of scope for most sUAS operations
Vision and night-specific effects
Factors affecting vision, glare, sun angle, scanning technique, matter directly because maintaining visual line of sight depends entirely on the pilot's eyes doing their job. Night operations add their own specific physiological wrinkle: dark adaptation takes real time, and night illusions like autokinesis, a stationary light appearing to drift against a featureless dark background, can make a pilot second-guess something that hasn't actually moved.
Fitness for flight ties all of this together as a standing question, not a one-time check. A pilot who was fine at the start of a long, hot operation may not still be fine two hours in, and the physiological factors here are the reason why re-assessing mid-operation is a real practice, not just preflight boilerplate.
How the exam actually uses this
Physiology questions tend to describe a symptom or a scenario, tingling fingers and lightheadedness during a stressful flight, a pilot two hours into a hot-day operation, and ask what's most likely happening or what the pilot should do about it. Recognizing the described symptom pattern matters more here than memorizing a list of terms in the abstract.
Full breakdown and drills for this area are in the handbook.
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